The latest American model forecast has a major storm system impacting the Midwest, Great Lakes and South US. As of now, the latest American GFS model has a solid snowstorm hitting southeast Minnesota, portions of Wisconsin, portions of Iowa and even into southeast Nebraska. This would be 'heart-attack snow' event, in that the snow would be very heavy due to marginal temperatures. As of now, the European model does not have this timeframe within its forecast period- we will need a few more days before that model can grasp the April 5-7 time period and confirm or deny this potential storm system.
Current thinking on this system is that there is potential- the long range looks to have an active Pacific jet stream, something that could enhance storm chances and storm strength if the storm were to happen.